Changes in version 0.0.6 (2026-04-15) New features Data and Quantum Encoding Added curated datasets that support reproducible workflows for quantum state preparation and Hamiltonian construction in immunometabolic modeling: - data_enc: biomarker panel for 3-qubit angle encoding. - data_corr: biomarker pool for Hamiltonian correlation structure. Changes in version 0.0.5 (2025-11-09) New features Quantum Key Distribution (QKD) Protocols - Added full simulation of the BB84 protocol through run_bb84_simulation(). This function models the quantum key distribution process between Alice and Bob, computing the Quantum Bit Error Rate (QBER) under both perfect (secure) and eavesdropped (compromised) channels. - Added simulation of the E91 (Ekert 1991) entanglement-based protocol via run_e91_simulation(). This implementation uses Bell’s inequality (CHSH statistic) to determine whether the communication channel exhibits quantum behavior (|S| > 2) or classical (insecure) behavior (|S| ≤ 2). Interaction and Payoffs Framework - Improved integration between Interaction and InteractionClassification objects. - Enhanced the payoff computation workflow, introducing mse.payoffs() for evaluating mean squared errors between observed and predicted payoffs. - Updated internal accessors to reduce direct exposure of object internals, ensuring cleaner S3 method dispatch and reproducibility. Documentation and Testing - Expanded documentation with detailed Roxygen examples and theoretical references for both BB84 and E91 protocols. - Added reproducible test cases and numerical rounding stability in snapshot tests. - Improved code consistency and formatting to support reproducible builds on CRAN. Changes in version 0.0.4 (2025-05-20) New features Interaction - Added new functionalities to the Interaction class, enhancing its capabilities for modeling quantum simulations. InteractionClassification - Added new functionalities to the InteractionClassification class. Quantum game of phenotypes - Added new fubnctionalities to design and simulate quantum games of HIV phenotypes